The human mucus varies chemically and structurally over three domains: across itself - apical-basolateral axis, between the different body districts - lung, stomach, intestine, cervico-vaginal, among others, and between states - physiological or pathological, fed or fasting, ovulation or pregnancy. Some mucus contain a gradient of oxygen and nutrients which deeply affects bacteria behaviour. These conditions where taken into account as a target while developing each Bac3Gel model.

The human mucus functions as a filter for any agent that is able to reach it and attempts to cross it. The objective is to protect the epithelium and the whole system from harmful substances and pathogens. It works in tandem with the immune system by entrapping and expelling harmful agents. Sometimes micro-organisms and human cells suffer necrosis and release DNA across the mucus influencing it behaviour, mucus models should be able account for it.

The human mucus varies chemically and structurally over three domains: across itself - apical-basolateral axis, between the different body districts - lung, stomach, intestine, cervico-vaginal, among others, and between states - physiological or pathological, fed or fasting, ovulation or pregnancy. Some mucus contain a gradient of oxygen and nutrients which deeply affects bacteria behaviour. These conditions where taken into account as a target while developing each Bac3Gel model.

The human mucus functions as a filter for any agent that is able to reach it and attempts to cross it. The objective is to protect the epithelium and the whole system from harmful substances and pathogens. It works in tandem with the immune system by entrapping and expelling harmful agents. Sometimes micro-organisms and human cells suffer necrosis and release DNA across the mucus influencing it behaviour, mucus models should be able account for it.